What cocktail includes muddled cherry and orange?

The cocktail that includes muddled cherry and orange is the Muddled Old Fashioned. This classic cocktail is characterized by its preparation method, which involves mashing or muddling the fruit, typically a cherry and an orange slice, with sugar and bitters before adding bourbon or rye whiskey. The muddling process releases the flavors of the fruits, enhancing the drink's character. This traditional approach to making an Old Fashioned is integral to its taste profile, setting it apart from other cocktails that do not include muddled fruit in their preparation.

The other options listed do not include muddled cherry and orange as significant components or preparation techniques. The Screwdriver is primarily made with vodka and orange juice; the White Russian combines vodka, coffee liqueur, and cream, and the Grasshopper is a dessert cocktail made with crème de menthe, crème de cacao, and cream.